Figure 3

Inhibition or enhancement of the TPA-induced activation of AP-1 by substituted trans -stilbenes devoid of hydroxy or methoxy functional groups. Screening with the 293/AP-1-luc cell of a range of substituted trans-stilbenes, which do not have hydroxyl or methoxy functional groups, demonstrated that some derivatives inhibit, some enhance and others have no effects on the TPA-induced activation of AP-1. The * notation indicates p < 0.01.