Table 2 Comparison of desipramine-treated and control rat rectal temperatures at various times after the last dose of desipramine in the 4-day treatment paradigm.

14 h

34.4 ± 0.2 (4)

34.6 ± 0.4 (4)

14 h

34.2 ± 0.2 (3)

33.6 ± 0.2^a (5)

24 h

34.4 ± 0.2 (12)

34.5 ± 0.1 (12)

24 h

33.9 ± 0.1 (14)

33.6 ± 0.2 (12)

48 h

35.3 ± 0.2 (14)

33.9 ± 0.1^a (13)

63 h

35.3 ± 0.1 (11)

35.3 ± 0.3 (14)

96 h

34.7 ± 0.2 (8)

34.3 ± 0.1 (7)

96 h

35.0 ± 0.1 (13)

34.9 ± 0.2 (9)