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Table 1 Results for oral clearance (OC) models

From: Structure-activity models of oral clearance, cytotoxicity, and LD50: a screen for promising anticancer compounds

Model Task Kernel Features Average test set precision, (+) labels Average test set precision, (-) labels
OC.1 oral clearance Gaussian subset 0.649 (0.060) 0.569 (0.111)
OC.2 oral clearance linear subset 0.606 (0.071)* 0.547 (0.107)**
OC.3 oral clearance & bioavailability Gaussian subset 0.636 (0.060) 0.625 (0.091)
OC.4 oral clearance & bioavailability Gaussian all features 0.626 (0.066) 0.634 (0.108)***
OC.5 oral clearance & bioavailability linear subset 0.635 (0.061) 0.637 (0.093)
  1. * Significant differences by ANOVA (p < 0.05): OC.1 vs. OC.2
  2. ** Significant differences by ANOVA (p < 0.05): OC.2 vs. OC.3, OC.4, and OC.5 when testing OC.1 through OC.5
  3. *** Significant differences by ANOVA (p < 0.05): OC.4 vs. OC.1 when testing OC.1, OC.3, and OC.4