Figure 2
From: Pharmacological Properties of DOV 315,090, an ocinaplon metabolite
Pharmacokinetics of ocinaplon and DOV 315,090. Blood levels of ocinaplon (●,○) and DOV 315090 (▲,△) were determined at various times after i.v. (●,▲) or oral (○,△) administration of 5 mg/kg ocinaplon to rats. Plotted results do not include one animal that exhibited a low blood level (0.47 μg/ml) of ocinaplon at the initial 10 min time point after oral administration and proportionally lower levels of both compounds throughout the duration of the experiment. This animal may have regurgitated a portion of the dose (of the suspension).