Skip to main content
Figure 1 | BMC Pharmacology

Figure 1

From: Effects of BAY 41–2272 on smooth muscle tone, soluble guanylyl cyclase activity and NADPH oxidase activity/expression in corpus cavernosum from wild-type, neuronal and endothelial NOS null mice

Figure 1

(a) Concentration-response curves to BAY 41–2272 (0.01–10 μM) in CC from wild-type (WT), eNOS and nNOS knockout animals (n = 6); (b) Formation of cGMP under basal conditions and after stimulation by BAY 41–2272 (0.001–1 μM) in crude protein extracts of cavernosal tissue; (c) Inhibitory effect of BAY 41–2272 (0.01–0.1 μM) on superoxide formation elicited by incubation of CC with U46619 over a 8 h period.

Back to article page

BMC Pharmacology

ISSN: 1471-2210