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Figure 1 | BMC Pharmacology

Figure 1

From: Pharmacological characterization of the novel phosphodiesterase type 5 (PDE5) inhibitor lodenafil carbonate on human and rabbit corpus cavernosum

Figure 1

(a) Structure of lodenafil carbonate; (b) Concentration-response curves to lodenafil carbonate (0.001–100 μM) in rabbit (closed circles) and human (open circles) CC; (c) Effect of lodenafil carbonate on cyclic GMP hydrolysis; (d, e) Mean plasma concentrations of lodenafil carbonate, lodenafil and demethylsildenafil in Beagle dogs after single intravenous (1 mg/kg; top) and oral (10 mg; bottom) doses of lodenafil carbonate.

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BMC Pharmacology

ISSN: 1471-2210