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Table 2 24-h urinary chloride (Cl-) excretion data and K+/Cl- ratio in male and female control and NaVPA-rat groups (mean ± SD)

From: Sodium valproate stimulates potassium and chloride urinary excretion in rats: gender differences

Rat groups n 24-h Cl- level (mmol/l) 24-h Cl- excretion (mmol/24 h) 24-h Cl- excretion per 100 g body weight (mmol/100 g) Cl-/creatinine ratio K+/Cl- ratio
Control rats       
females 14 104 ± 51 0.886 ± 0.40 0.371 ± 0.15 12.6 ± 6.9 1.30 ± 0.44
males 14 168 ± 128 1.164 ± 0.70 0.420 ± 0.26 14.2 ± 8.8 1.15 ± 0.54
NaVPA-rats       
females 13 180 ± 60 1.997 ± 0.52 * 0.833 ± 0.22 * 24.6 ± 4.7 * 0.49 ± 0.12
males 13 275 ± 184 3.396 ± 1.21 * 1.208 ± 0.53 * 34.6 ± 16.5 * 0.45 ± 0.22
  1. – Statistically significant difference, as compared to control group (p < 0.05).
  2. * – Statistically significant difference versus the other gender (p < 0.05).