From: Sodium valproate stimulates potassium and chloride urinary excretion in rats: gender differences
Rat groups | n | 24-h Cl- level (mmol/l) | 24-h Cl- excretion (mmol/24 h) | 24-h Cl- excretion per 100 g body weight (mmol/100 g) | Cl-/creatinine ratio | K+/Cl- ratio |
---|---|---|---|---|---|---|
Control rats | ||||||
females | 14 | 104 ± 51 | 0.886 ± 0.40 | 0.371 ± 0.15 | 12.6 ± 6.9 | 1.30 ± 0.44 |
males | 14 | 168 ± 128 | 1.164 ± 0.70 | 0.420 ± 0.26 | 14.2 ± 8.8 | 1.15 ± 0.54 |
NaVPA-rats | ||||||
females | 13 | 180 ± 60• | 1.997 ± 0.52• * | 0.833 ± 0.22• * | 24.6 ± 4.7• * | 0.49 ± 0.12• |
males | 13 | 275 ± 184• | 3.396 ± 1.21• * | 1.208 ± 0.53• * | 34.6 ± 16.5• * | 0.45 ± 0.22• |