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Table 1 Diuresis and 24-h urinary K+ excretion in male and female control and NaVPA-rat groups (mean ± SD)

From: Sodium valproate stimulates potassium and chloride urinary excretion in rats: gender differences

Rat groups n 24-h diuresis (ml) 24-h K+ level (mmol/l) 24-h K+ excretion (mmol) 24-h K+ excretion per 100 g body weight (mmol) K+/creatinine ratio
Control rats       
females 14 9.1 ± 2.3 116 ± 27 1.01 ± 0.17 0.43 ± 0.06* 13.9 ± 3.38
males 14 8.0 ± 2.1 135 ± 29 1.04 ± 0.18 0.37 ± 0.08* 12.7 ± 7.9
NaVPA-rats       
females 13 12.1 ± 4.1 84 ± 28 0.93 ± 0.14* 0.39 ± 0.06 11.8 ± 2.34
males 13 16.0 ± 7.2 93 ± 30 1.32 ± 0.26 * 0.44 ± 0.08 12.4 ± 2.88
  1. – Statistically significant difference as compared to control group (p < 0.05).
  2. * – Statistically significant difference versus the other gender (p < 0.05).