From: Sodium valproate stimulates potassium and chloride urinary excretion in rats: gender differences
Rat groups | n | 24-h diuresis (ml) | 24-h K+ level (mmol/l) | 24-h K+ excretion (mmol) | 24-h K+ excretion per 100 g body weight (mmol) | K+/creatinine ratio |
---|---|---|---|---|---|---|
Control rats | Â | Â | Â | Â | Â | Â |
females | 14 | 9.1 ± 2.3 | 116 ± 27 | 1.01 ± 0.17 | 0.43 ± 0.06* | 13.9 ± 3.38 |
males | 14 | 8.0 ± 2.1 | 135 ± 29 | 1.04 ± 0.18 | 0.37 ± 0.08* | 12.7 ± 7.9 |
NaVPA-rats | Â | Â | Â | Â | Â | Â |
females | 13 | 12.1 ± 4.1• | 84 ± 28• | 0.93 ± 0.14* | 0.39 ± 0.06 | 11.8 ± 2.34 |
males | 13 | 16.0 ± 7.2• | 93 ± 30• | 1.32 ± 0.26• * | 0.44 ± 0.08• | 12.4 ± 2.88 |