Figure 1
From: Structural and functional definition of the specificity of a novel caspase-3 inhibitor, Ac-DNLD-CHO
Inhibitory effects of caspase-3 inhibitors on caspases. Human recombinant caspase-3 (A), caspase-7 (B), caspase-8 (C), and caspase-9 (D) were preincubated for 10 min with indicated concentrations of Ac-DNLD-CHO (●), Ac-DEVD-CHO (○), Ac-DQTD-CHO (△), or Ac-DMQD-CHO (□), and then the activities of the caspases were measured with each substrate as described in ''Methods''. The kinetics data presented are the means of three independent experiments.