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Table 1 Administration of hypotonic and isotonic ciclesonide suspensions and nasal tissue sampling.

From: Uptake and metabolism of ciclesonide and retention of desisobutyryl-ciclesonide for up to 24 hours in rabbit nasal mucosa

Suspension administered

Animals, n *

Dose per animal, μg

Volume per actuation, μL

Sampling time, h

Hypotonic ciclesonide

4

143

100

0.5, 2, 4

Isotonic ciclesonide

4

143

100

0.5, 2, 4

Hypotonic ciclesonide

5

143

100

0.5, 8, 12, 16, 24

  1. * = Represents the number of animals per sampling time.
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BMC Pharmacology

ISSN: 1471-2210