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Table 1 Change of PPT due to Vehicle and Various Antagonists during a Period of 20 min

From: The enantiomers of tramadol and its major metabolite inhibit peristalsis in the guinea pig small intestine via differential mechanisms

  

Δ PPT (Pa)

Vehicle (Tyrode's solution)

n = 54

0.31 ± 1.9

Naloxone (0.5 μM)

n = 18

-10.4 ± 1.6

Methysergide (1 μM) + tropisetron (1 μM)

n = 18

13.4 ± 2.5

Yohimbine (1 μM) + prazosin (1 μM)

n = 18

3.0 ± 2.0

  1. Data represent means ± SEM