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Table 2 Correlation of SH-SY5Y cell α2-AR p K i values with those of native and cloned α2-AR subtypes.

From: The presence of β2-adrenoceptors sensitizes α2A-adrenoceptors to desensitization after chronic epinephrine treatment

Comparison

Reference

# of Values Compared

Correlation Coefficient

Slope

p value

v. HT29

21,22

6

0.93

1.48 ± 0.41

0.07

v. NG108-15

21

6

0.13

0.17 ± 0.91

0.87

v. OK

21,22

6

0.62

0.99 ± 0.73

0.27

v. α2C10

23

6

0.80

1.04 ± 0.45

0.10

v. α2C2

23

6

0.40

0.48 ± 0.65

0.50

v. α2C4

23

6

0.70

0.94 ± 0.52

0.16

v. BE(2)-C

6

6

0.98*

1.38 ± 0.18

0.01

  1. Correlation coefficient values (r) were generated by comparing p K i values from Table 1 with previously published values for one-site models using Pearson correlation analysis (GraphPad Prism). The slope of the linear regression line is also included. Correlations were considered significant (*) if p ≤ 0.05.