BMC Pharmacology

Table 1 A comparison of areas under the ROC curves between NSCLC and SCLC at various time post drug administration.

From: Chlorin e6 – polyvinylpyrrolidone mediated photosensitization is effective against human non-small cell lung carcinoma compared to small cell lung carcinoma xenografts

Time post Ce6 – PVP administration, h	NSCLC		SCLC
	Area under the ROC curve	P value	Area under the ROC curve	P value
0.5	0.52	0.9024	0.52	0.9025
1	0.68	0.2704	0.70	0.2207
2	0.66	0.3272	0.68	0.2704
3	0.88	0.0200*	0.70	0.2207
4	0.94	0.0071*	0.74	0.1417
5	0.90	0.0143*	0.58	0.6242

An area of 1 represents a perfect discrimination of tumor from normal tissue; an area of 0.5 represents no discrimination between normal and abnormal. The P value indicates whether the area under the ROC is significantly different from 0.5. *If the P value is < 0.05, the area under the ROC curve is significantly different (see description of statistical analysis). For tumors, each point represents a mean of 5 eggs whereas for normal, each point represents a mean of 10 eggs.

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