Figure 5From: Chlorin e6 – polyvinylpyrrolidone mediated photosensitization is effective against human non-small cell lung carcinoma compared to small cell lung carcinoma xenograftsA morphologic study of NSCLC and SCLC tumor damage efficiency using the method of vital staining with Evans blue at 48 h post Ce6-PVP mediated PDT. Strong homogeneous staining was observed in the untreated controls (Fig. 5A, B), whereas in the treated tumor at 3 h drug-light interval (DLI) (Fig 5C, D) and at 6 h DLI (Fig 5E, F). Tissues damage was clearly distinguishable as an unstained area in the the tumor. Drug dose: 2.0 mg/kg; light dose: 150 J/cm2; 125 mW/cm2. Each data point is an average of at least 5 animals, Bars = standard error of the mean. *The mean difference is significant at the 0.05 level compared to the NSCLC group.Back to article page