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Table 1 Mean Cmax of etoposide (VP16) and ifosfamide administered alone or with imatinib

From: Impact of imatinib on the pharmacokinetics and in vivo efficacy of etoposide and/or ifosfamide

 

Ifosfamide

Ifosfamide+ imatinib

Mean Cmax

9 +/- 4.5 μg/ml

14.4 +/- 6.4 μg/ml

 

Etoposide

Etoposide + imatinib

Mean Cmax

8.6 +/- 4.1 μg/ml

42.7 +/- 37.6 μg/ml