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Figure 2 | BMC Pharmacology

Figure 2

From: Gene expression profiling reveals effects of Cimicifuga racemosa (L.) NUTT. (black cohosh) on the estrogen receptor positive human breast cancer cell line MCF-7

Figure 2

Proliferation assay: Effects on growth rate of MCF-7 cells. MCF-7 cells were treated with (A) dichloromethane extract of black cohosh rhizome, (B) actein or (C) mixture of aglycons derived from cycloartane glycosides. Controls (100% proliferation) contained 0.1% DMSO. After 120 h cell number was determined by MTT dye-reduction assay. Relative proliferation data are presented as means ± SD (n = 3–6). *p < 0.05, **p < 0.01, ***p < 0.001 vs. control (Student's t-test).

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