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Figure 7 | BMC Pharmacology

Figure 7

From: A comparative study of the actions of alkylpyridinium salts from a marine sponge and related synthetic compounds in rat cultured hippocampal neurones

Figure 7

Synthetic compounds 1–4 produced smaller changes in intracellular Ca2+ compared to poly-APS. A) Bar chart showing mean percentage changes in fluorescence compared to baseline values. Samples 1, 2 and 3 produced modest changes in intracellular Ca2+ that were significantly smaller than those seen with poly-APS (*P < 0.05, **P < 0.01 & ***P < 0.001). Sample 4 at a concentration of 5 μg/ml gave a similar response to 0.5 μg/ml poly-APS. B) Example traces of mean responses to the synthetic compounds and poly-APS. Each trace is comprised of the mean from 17–34 neurones.

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BMC Pharmacology

ISSN: 1471-2210