Figure 1

Graph showing the effects of daily oral administration of 6-shogaol (6.2 mg/Kg/day), indomethacin (2 mg/Kg/day) and peanut oil (0.2 ml/day-control) on the development (over 28 days) of edematous swelling of the knee induced by a single dose of CFA (0.5 ml of 1 mg/ml) in the synovial cavity of rats. Each data point represents the mean ± SEM value from 6 animals. Asterisks indicate values significantly different from the peanut oil control (* p ≤ 0.0002, ** p < 0.00008)