Skip to main content
Figure 3 | BMC Pharmacology

Figure 3

From: A pyridinium derivative from Red Sea soft corals inhibited voltage-activated potassium conductances and increased excitability of rat cultured sensory neurones

Figure 3

Comparison of electrophysiological activity between a single firing DRG neurone and a multiple firing DRG neurone. A) Traces showing the single action potential firing of a DRG, stimulated with 200, 400 and 600 pA depolarizing step commands and a prolonged 500 ms stimulus. B) Line graph illustrating the effect of increasing current commands on both single (blue line) and multiple action potential firing (red line) DRG neurones. C) Traces showing the effects of increasing stimulus amplitude (100–400 pA) on a multiple action potential firing DRG neurone. An increase in stimulus amplitude leads to an increase in the number of action potentials. In all cases the DRG neurones were held at -70 mV before stimulation.

Back to article page

BMC Pharmacology

ISSN: 1471-2210