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Figure 10 | BMC Pharmacology

Figure 10

From: A pyridinium derivative from Red Sea soft corals inhibited voltage-activated potassium conductances and increased excitability of rat cultured sensory neurones

Figure 10

Extract from Sarcophyton glaucum (100 μg/mL) did not cause a change in steady state inactivation but does show some activity dependence. A) Line graph showing mean control steady state currents (± s.e.m) activated from holding potentials between -100 and -10 mV by voltage step commands to +30 mV (blue) and the steady state inactivation relationship after application of c.Sg (n = 6). B) Line graph showing the normalised mean steady state inactivation plots under control conditions (blue) and after the application of c.Sg (n = 6). For each plot the current values were normalized with respect to the maximum outward current. C) The effect of a 1 s, 5 s and 10 s delays between concurrent voltage step commands on the net K+ outward current (at + 30 mV) during application of c. Sg (100 μg/mL).

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BMC Pharmacology

ISSN: 1471-2210