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Table 1 Effect of different doses of Hesperidin on CCl4 induced rise in AST, ALT and total bilirubin.

From: Hesperidin, a citrus bioflavonoid, decreases the oxidative stress produced by carbon tetrachloride in rat liver and kidney

  ALT (IU/L) AST(IU/L) Bilirubin total (mg/dl)
Control 100 100 100
CCl 4 255.55 ± 23.66a 444.44 ± 22.56a 205.21 ± 11.66a
HDN (200) 112.81 ± 13.66 126.66 ± 28.66 108.15 ± 9.66
CCl 4 +HDN (100) 185.18 ± 17.56a,b 333.33 ± 29.66a,b 176.63 ± 15.29a,b
CCl 4 +HDN (200) 144.44 ± 15.22a,b,c 244.44 ± 22.66a,b,c 149.45 ± 12.45a,b,c
  1. Values are expressed as percent response compared to control rats. a = Statistical significant at P < 0.05 as compare to control, b = Statistical significant at P < 0.05 as compare to CCl4, c = Statistical significant at P < 0.05 as compare to CCl4+ HDN(100)