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Table 1 Effect of intravenous administration of oxybutynin on cystometrographic parameters in anesthetized rats

From: Urodynamic effects of oxybutynin and tolterodine in conscious and anesthetized rats under different cystometrographic conditions

  BVC (ml) TP (mmHg) MP (mmHg) HFO (number) HFO (amplitude)
Controls      
Before 0.47 ± 0.04 4.74 ± 0.55 25.0 ± 3.6 4.2 ± 0.2 1.82 ± 0.19
After 0.47 ± 0.04 4.88 ± 0.58 20.9 ± 2.0 4.6 ± 0.2 1.63 ± 0.11
Oxybutynin 0.3 mg/kg      
Before 0.44 ± 0.11 3.44 ± 0.84 20.3 ± 2.3 4.6 ± 0.2 1.68 ± 0.27
After 0.27 ± 0.05 2.34 ± 0.51 15.5 ± 1.7 ** 4.2 ± 0.7 1.63 ± 0.24
  1. Data are expressed as mean ± s.e. mean. BVC: bladder volume capacity; TP: threshold pressure; MP: micturition pressure; HFO: high frequency oscillations (number and amplitude). * = p < 0.05; ** = p < 0.01 before vs after administration (Student's t test).