Skip to main content

Table 3 Dose- response relations between anti-cancer drugs for cytotoxic effect against human leukemia cell line HL-60 for 24 h; * P < 0.01; n = 3;

From: Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines

Compounds Concentrations OD values Mean ± SD Percentage inhibition %
Control -- 1.229 ± 0.125 --
Probimane 10.0 0.298 ± 0.010* 75.6
  2.0 0.260 ± 0.005* 78.9
  0.4 1.142 ± 0.010 7.1
  0.08 1.199 ± 0.012 2.4
Doxorubicin 10.0 0.256 ± 0.021* 79.2
  2.0 0.266 ± 0.013* 78.3
  0.4 0.312 ± 0.016* 74.5
  0.08 0.408 ± 0.031* 66.9
5-Fluorouracil 5.0 0.421 ± 0.021* 65.6
  1.0 0.518 ± 0.012* 57.9
  0.2 0.585 ± 0.025* 54.4
  0.04 0.892 ± 0.038* 27.5
Vincristine 5.0 0.425 ± 0.010* 65.4
  1.0 0.423 ± 0.009* 65.6
  0.2 0.401 ± 0.009* 67.4
  0.04 0.394 ± 0.012* 68.0