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Table 2 Cytotoxic effects of anticancer drugs against tumor cell lines in vitro; drug exposure for 48 h

From: Anti-proliferative effects, cell cycle G2/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines

Compounds IC50 μM
  P388 HL-60 HeLa
Doxorubicin 11.7 0.005 1.12
Vincristine No effect 0.05 4.56
5-fluorouracil 22.6 0.04 0.23
Probimane 64.6 1.97 5.12
ICRF-187 64.0 3.73 129
MST-16 5.23 33.4 26.4