BMC Pharmacology

Table 2 Cytotoxic effects of anticancer drugs against tumor cell lines in vitro; drug exposure for 48 h

From: Anti-proliferative effects, cell cycle G₂/M phase arrest and blocking of chromosome segregation by probimane and MST-16 in human tumor cell lines

Compounds	IC₅₀ μM
	P388	HL-60	HeLa
Doxorubicin	11.7	0.005	1.12
Vincristine	No effect	0.05	4.56
5-fluorouracil	22.6	0.04	0.23
Probimane	64.6	1.97	5.12
ICRF-187	64.0	3.73	129
MST-16	5.23	33.4	26.4

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