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Table 3 Effects of the aqueous extract from Cissus sicyoides (AECS) on biochemical parameters in the blood from alloxan-induced diabetic rats

From: Hypoglycemic and anti-lipemic effects of the aqueous extract from Cissus sicyoides

Parameter Group
  Control AECS 100 mg/kg AECS 200 mg/kg
Glucose (mg/dL)    
   Before 264.8 ± 12.66 252.2 ± 8.44 250.8 ± 10.74
   After 248.1 ± 11.65 218.1 ± 16. 21 188.0 ± 16.22*
Cholesterol (mg/dL)    
   Before 58.4 ± 3.92 56.6 ± 3.19 63.0 ± 2.55
   After 55.4 ± 2.91 50.1 ± 5.89 54.6 ± 2.29
Triglycerides (mg/dL)    
   Before 169.8 ± 8.61 256.4 ± 24.60 165.4 ± 12.87
   After 124.1 ± 8.02 * 132.5 ± 9.02 * 86.4 ± 7.56 *
ALT (IU/l)    
   Before 20.0 ± 1.33 28.6 ± 2.15 20.8 ± 1.62
   After 34.7 ± 2.89 * 41.2 ± 2.71 * 29.8 ± 2.22
AST (IU/l)    
   Before 60.5 ± 3.90 62.2 ± 5.52 75.9 ± 4.74
   After 85.5 ± 4.35 * 89.3 ± 7.03 * 88.3 ± 3.73
  1. Values are means ± SEM of 8 to 18 animals per group. The blood was collected from the orbital sinus, 48 h after the alloxan administration, 60 mg/kg, i.v., before and 1 h after the last administration of distilled water (controls) or AECS, daily for 4 days. *p < 0.05 as compared to the same group, 48 h after the alloxan injection (ANOVA and Tukey as the post hoc test).