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Table 3 Effects of the aqueous extract from Cissus sicyoides (AECS) on biochemical parameters in the blood from alloxan-induced diabetic rats

From: Hypoglycemic and anti-lipemic effects of the aqueous extract from Cissus sicyoides

Parameter

Group

 

Control

AECS 100 mg/kg

AECS 200 mg/kg

Glucose (mg/dL)

   

   Before

264.8 ± 12.66

252.2 ± 8.44

250.8 ± 10.74

   After

248.1 ± 11.65

218.1 ± 16. 21

188.0 ± 16.22*

Cholesterol (mg/dL)

   

   Before

58.4 ± 3.92

56.6 ± 3.19

63.0 ± 2.55

   After

55.4 ± 2.91

50.1 ± 5.89

54.6 ± 2.29

Triglycerides (mg/dL)

   

   Before

169.8 ± 8.61

256.4 ± 24.60

165.4 ± 12.87

   After

124.1 ± 8.02 *

132.5 ± 9.02 *

86.4 ± 7.56 *

ALT (IU/l)

   

   Before

20.0 ± 1.33

28.6 ± 2.15

20.8 ± 1.62

   After

34.7 ± 2.89 *

41.2 ± 2.71 *

29.8 ± 2.22

AST (IU/l)

   

   Before

60.5 ± 3.90

62.2 ± 5.52

75.9 ± 4.74

   After

85.5 ± 4.35 *

89.3 ± 7.03 *

88.3 ± 3.73

  1. Values are means ± SEM of 8 to 18 animals per group. The blood was collected from the orbital sinus, 48 h after the alloxan administration, 60 mg/kg, i.v., before and 1 h after the last administration of distilled water (controls) or AECS, daily for 4 days. *p < 0.05 as compared to the same group, 48 h after the alloxan injection (ANOVA and Tukey as the post hoc test).