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Figure 3 | BMC Pharmacology

Figure 3

From: A novel method for evaluation and screening of caspase inhibitory peptides by the amino acid positional fitness score

Figure 3

APF score matrices of caspases. The APF score matrices indicate the interaction preferences of amino acids with (a) caspase-3, (b) caspase-7, (c) caspase-8, and (d) caspase-9 at each position (P4-P2). If an APF score is greater than 0, the amino acid tends to be favored at a given position. ΔGth (threshold value of ΔGbind) of caspases-3, -7, -8, and -9 are -11.05, -10.69, -11.03, and -12.12 kcal/mol, respectively.

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BMC Pharmacology

ISSN: 1471-2210