Figure 5
From: Inhibition of pancreatic cholesterol esterase reduces cholesterol absorption in the hamster
Inhibitors of pancreatic cholesterol esterase have the potential to modify cholesterol metabolism at multiple sites. In this model, cholesterol esterase is proposed to contribute to the availability of free cholesterol by catalyzing the hydrolysis of cholesterol esters and contribute to the formation of lysolecithin-containing micelles, which are the vehicles for efficient absorption of cholesterol, by catalyzing the hydrolysis of lecithin.