From: Antitumor effects of two bisdioxopiperazines against two experimental lung cancer models in vivo
Compounds | Dosage | Schedule | Tumor weight | Tumor Inhibition |
---|---|---|---|---|
mg/kg | 1, 5, and 9 administration | (g) | % | |
Control | -- | -- | 2.46 ± 0.06 | |
Razoxane (Raz) | 10 | 3 times a day* | 1.44 ± 0.07 | 41.5 |
Bleomycin (Ble) | 15 | 1 time a day | 1.50 ± 0.06 | 39.0 |
Raz + Ble | 10 + 15 | 3 times + 1 time a day | 0.66 ± 0.05** | 73.2** |