Figure 1From: Characterisation of cytotoxicity and DNA damage induced by the topoisomerase II-directed bisdioxopiperazine anti-cancer agent ICRF-187 (dexrazoxane) in yeast and mammalian cellsClonogenic sensitivity of PRR defective Δrad6 and Δrad18 yeast cells towards equitoxic doses of ICRF-187 and m-AMSA. A Δrad52 strain is included for comparison. Error-bars represent SEM of at least 3 experiments.Back to article page