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Figure 1 | BMC Pharmacology

Figure 1

From: Reduced inhibitory action of a GABAB receptor agonist on [3H]-dopamine release from rat ventral tegmental area in vitro after chronic nicotine administration

Figure 1

Photomicrograph of a representative coronal section of rat brain labelled with a polyclonal antibody directed against tyrosine hydroxylase. The picture shows the orientation of the cuts (dark lines) for the dissection of the ventral tegmental area (VTA). The basal cerebral peduncle (Cp) was used as a visual landmark to obtain the coronal section containing the VTA. To remove the substantia nigra (pars compacta, SNC, and reticulata, SNR) from this slice, two transversal cuts were made along the medial lemniscus (Ml) on either side. Finally, the VTA was dissected out by making a horizontal cut 1.5 mm dorsal to the ventral edge of the section and stripped of the interpeduncular nucleus (IP) by cutting 0.5 mm above the same edge. Scale bar is 1 mm.

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BMC Pharmacology

ISSN: 1471-2210