Figure 4

Different responses to pregabalin were observed in different populations of cultured DRG neurones. Bar chart showing the distribution of neurones with different cell soma areas and the response to pregabalin. The distributions for intermediate and larger neurones where pregabalin (25 μM) increased K⁺-evoked Ca²⁺ influx are shown in black bars. The distributions for small and some intermediate neurones where pregabalin (25 μM) attenuated K⁺-evoked Ca²⁺ influx are shown in open bars.