Figure 1

Conentration-dependent effect of thymol on the Ca current. A: Superimposed I_Ca traces elicited by 800 ms long depolarizations to +10 mV in a muscle fiber before and after cumulative application of 100, 200, 300, and 600 μM thymol. B: Average of peak I_Ca normalized to control as a function of the thymol concentration. The solid line represents the Hill fit of the averaged curve. Symbols and bars represent mean ± SEM values obtained from 8 preparations, asterisks denote significant (P < 0.05) changes from control values.