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Figure 3 | BMC Pharmacology

Figure 3

From: The protective effect of M40401, a superoxide dismutase mimetic, on post-ischemic brain damage in Mongolian gerbils

Figure 3

Panel A. Representative histological examination of brain hippocampus of Mongolian gerbil's showing significant neuronal loss within CA1 area, compared to sham operated animals, when evaluated 7 days after induction of BCCO. Panel B shows quantitative analysis for CA1 hippocampal neurons detected in sham-operated and BCCO-operated animals either untreated or treated with M40401. In particular, M40401 (40 mg/Kg given i.p. 1 h after BCCO; n = 10) showed protective effect against ischemia-reperfusion-induced reduction of neuronal cell number detected within CA1 hippocampal area.

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