Table 2 Effect of nimesulide (NIM) on total sulfhydryl groups (TSH) and non-protein sulfhydryl groups (NPSH) following 20 min incubation with 12 mM kainic acid (KA).

Control

23.97 ± 0.25 **

1.85 ± 0.03 **

KA

19.25 ± 0.35

1.61 ± 0.04

KA + NIM (0.1 mM)

18.72 ± 0.38

1.57 ± 0.03

KA + NIM (0.2 mM)

20.21 ± 0.56

1.64 ± 0.03

KA + NIM (0.4 mM)

20.25 ± 0.35

1.71 ± 0.02

KA + NIM (0.6 mM)

21.96 ± 0.46 *

1.76 ± 0.03 *

KA + NIM (0.8 mM)

22.67 ± 0.30 **

1.76 ± 0.01 *

KA + NIM (1.0 mM)

23.14 ± 0.15 **

1.78 ± 0.02 *

KA + NIM (1.2 mM)

23.03 ± 0.30 **

1.81 ± 0.04 **

KA + NIM (1.4 mM)

23.68 ± 0.25 **

1.79 ± 0.03 **

KA + NIM (1.6 mM)

24.03 ± 0.31 **

1.81 ± 0.02 **