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Table 1 Effect of different concentrations (1, 6 and 12 mM) of kainic acid (KA) on total sulfhydryl groups (TSH) and non-protein sulfhydryl groups (NPSH) following 20 min incubation with rat brain homogenates.

From: Effects of nimesulide on kainate-induced in vitro oxidative damage in rat brain homogenates

 

TSH (nmol/mg protein)

NPSH (μmol/g tissue)

Control

23.97 ± 0.25

1.85 ± 0.03

KA (1 mM)

22.97 ± 0.38

1.77 ± 0.05

KA (6 mM)

20.90 ± 0.27 *

1.65 ± 0.05 *

KA (12 mM)

19.25 ± 0.35 **

1.61 ± 0.04 **

  1. Values are means ± SEM of 3 experiments. *P < 0.05 and **P < 0.01 with respect to control.
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BMC Pharmacology

ISSN: 1471-2210