Table 3 Potentiation of the pentobarbital sleep with carbenoxolone in mice
From: Anticonvulsant, sedative and muscle relaxant effects of carbenoxolone in mice
Treatment | Dose | Latency (min) | Duration (min) |
|---|---|---|---|
Normal saline | 10 ml/kg | 7.28 ± 2.09 | 28.01 ± 1.88 |
Diazepam | 1 mg/kg | 4.67 ± 0.43** | 49.16 ± 4.67*** |
Carbenoxolone | 100 mg/kg | 4.33 ± 0.25** | 65.55 ± 5.06*** |
|  | 200 mg/kg | 4.24 ± 0.31** | 75.10 ± 7.34*** |
|  | 300 mg/kg | 3.63 ± 0.38*** | 93.32 ± 16.49*** |