Figure 1

NO output recordings, presented as values relative to baseline, during infusion of A: saline (150 mM NaCl) (n = 5), B: CGP 42112A at increasing infusion rates (0.01 μg kg ^-1 min^-1, 0.1 μg kg ^-1 min^-1,1.0 μg kg ^-1 min^-1) each lasting 45 min (n = 11), C: CGP 42112A (as in B) in the presence of PD123319 (0.3 mg kg^-1 iv bolus and 0.03 mg kg^-1 h^-1 iv infusion administration initiated at baseline) (n = 7). A p-value < 0.05 was concidered significant and is denoted by *.