Protection against acute adriamycin-induced cardiotoxicity by garlic: Role of endogenous antioxidants and inhibition of TNF-α expression

Table 1 TBA-RS, GSH, catalase, SOD and GPx in rat heart in different treatment groups

Group	TBA-RS (n mole/gm wet wt.)	GSH (μg/gm wet wt.)	CATALASE (U/mg protein)	SOD (U/mg protein)	GPx (U/mg protein)
CTR	203.03 ± 11.52	479.17 ± 40.76	49.49 ± 2.91	6.88 ± 0.79	0.193 ± 0.04
ADR	328.72 ± 34.76^ab	688.02 ± 12.17^ac	13.81 ± 3.70^ac	4.54 ± 0.53^aa	0.083 ± 0.002^aa
PRO+ADR	145.16 ± 13.13^d	507.46 ± 17.40^d	14.76 ± 1.99	6.21 ± 0.79	0.158 ± 0.03^a
G-250+ADR	103.40 ± 17.24^d	447.59 ± 18.55^d	25.12 ± 3.33^d	6.08 ± 1.72	0.149 ± 0.03^a
G-500+ADR	276.54 ± 19.60^b	629.52 ± 11.37^c	15.41 ± 3.21	7.61 ± 0.93^b	0.177 ± 0.01^d

All values are expressed as Mean ± SE (n = 6). p values: a < 0.05, b < 0.02, c < 0.01, d < 0.001 vs ADR and aa < 0.05, ab < 0.01, ac < 0.001 vs CTR. (One way ANOVA)