Figure 2

Effect of a subcutaneous injection of naloxone on the antinociceptive effect of intraperitoneally administered Crocus sativus petal ethanolic extract, morphine and diclofenac on acetic acid-induced writhing test in mice. Values are the mean ± S.E.M. of writhes number for 8 mice, ^***P<0.001, compared to control (normal saline); +++P<0.001, compared to morphine plus naloxone, Tukey-Kramer test.