From: 4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of all-trans retinal to all-trans retinoic acid by ALDH1A1, but not the differentiation of HL-60 promyelocytic leukemia cells exposed to all-trans retinal
IC50 of DPAB (μM)
Substrate
ALDH1A1
Mouse
Human
all-trans Retinal
0.11 ± 0.02
0.13 ± 0.03
Propanal
0.040 ± 0.01
0.14 ± 0.04
Phenylacetaldehyde
0.36 ± 0.04
1.2 ± 0.1