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Figure 2 | BMC Pharmacology

Figure 2

From: 4-(N,N-dipropylamino)benzaldehyde inhibits the oxidation of all-trans retinal to all-trans retinoic acid by ALDH1A1, but not the differentiation of HL-60 promyelocytic leukemia cells exposed to all-trans retinal

Figure 2

Differentiation response of HL-60 cells to retinoids and ALDH inhibitors. Retinoid concentrations were 1 μM for all-trans retinal (Ral) and all-trans retinoic acid (RA). Inhibitor concentrations were 50 μM for 4-(N,N-dipropylamino)benzaldehyde (DPAB) and 4-(N,N-diethylamino)benzaldehyde (DEAB). Control (black squares). Ral (red diamonds). RA (green circles). Ral + DPAB (dark blue triangles). RA + DPAB (hatched light blue squares). Ral + DEAB (hatched dark red diamonds).

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BMC Pharmacology

ISSN: 1471-2210