BMC Pharmacology

Table 1 Effects of various NO donors on stimulation evoked [³H]noradrenaline release and vasoconstriction in the rat tail arteries

From: Low molecular mass dinitrosyl nonheme-iron complexes up-regulate noradrenaline release in the rat tail artery

Treatment	n	S₄/S₂ ratio
		[³H]noradrenaline	Vasoconstriction
Control	7	1.08 ± 0.05	1.04 ± 0.06
DNIC-cysteine 3 μM	6	1.31 ± 0.06^**	0.25 ± 0.02^**
DNIC-thiosulfate 3 μM	6	1.38 ± 0.07^**	0.33 ± 0.04^**
Fe(II)-thiosulfate 10 μM	6	1.01 ± 0.03	0.92 ± 0.05
SNP 10 μM	7	1.04 ± 0.04	0.27 ± 0.06^**
Cys-NO 10 μM	7	1.08 ± 0.06	0.23 ± 0.02^**
GS-NO 10 μM	7	1.01 ± 0.03	0.27 ± 0.02^**

^**P < 0.01 in comparison to control arteries.

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