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Figure 1 | BMC Pharmacology

Figure 1

From: Low molecular mass dinitrosyl nonheme-iron complexes up-regulate noradrenaline release in the rat tail artery

Figure 1

Effect of DNIC-thiosulfate on electrical field stimulated [3H]noradrenaline release and vasoconstriction in the rat tail artery. Four periods (S1–S4) of electrical-field stimulation were delivered with intervals of 16 min. DNIC-thiosulfate was added 8 min before S3. The effect of DNIC-thiosulfate is presented as the ratio of change of [3H]noradrenaline in the perfusate or change of perfusion pressure evoked by S4 over S2. Each point represents the mean ± S.E.M. from 6–7 arteries. * P < 0.05 and ** P < 0.01 in comparison to control arteries.

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