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Table 8 Effects of the intraperitoneal administration of Anethum graveolens seed ethanolic extract and cimetidine on the pH and total gastric acid from pylorus-ligated mice

From: Effects of Anethum graveolens L. seed extracts on experimental gastric irritation models in mice

Treatment

Dose (g/kg)

pH

μEq H+

Saline

0.3 ml

3.76 ± 0.08

20.0 ± 0

Extract

0.5

4.45 ± 0.07***

5.0 ± 0***

Extract

2

5.05 ± 0.06***

5.0 ± 0***

Extract

3.5

5.51 ± 0.17***

2.5 ± 0***

Extract

5

6.07 ± 0.05***

2.5 ± 0***

Cimetidine

0.032

6.23 ± 0.07***

2.5 ± 0***

  1. Values are the mean ± S.E.M. of 6 mice, ***P < 0.001, Compared to control, Tukey-Kramer.