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Table 7 Effects of the intraperitoneal administration of Anethum graveolens seed aqueous extract and cimetidine on the pH and total gastric acid from pylorus-ligated mice

From: Effects of Anethum graveolens L. seed extracts on experimental gastric irritation models in mice

Treatment

Dose (g/kg)

pH

μEq H+

Saline

0.3 ml

3.73 ± 0.09

20.00 ± 0

Extract

0.05

3.96 ± 0.08***

7.08 ± 1.88***

Extract

0.18

4.43 ± 0.09***

5 ± 0***

Extract

0.32

5.04 ± 0.17***

2.5 ± 0***

Extract

0.45

5.58 ± 0.11***

2.5 ± 0***

Cimetidine

0.032

6.23 ± 0.06***

2.5 ± 0***

  1. Values are the mean ± S.E.M. of 6 mice, ***P < 0.001, Compared to control, Tukey-Kramer.