Selective alteration of gene expression in response to natural and synthetic retinoids.

Brand, Céline; Ségard, Pascaline; Plouvier, Pascal; Formstecher, Pierre; Danzé, Pierre-Marie; Lefebvre, Philippe

doi:10.1186/1471-2210-2-13

BMC Pharmacology

Table 1 Summary of newly identified ESTs and of known ESTs potentially regulated by retinoids.

From: Selective alteration of gene expression in response to natural and synthetic retinoids.

A) New sequences
Name	Homology	GenBank Accession Numbers	Northern
SRIG 23^, SRIG 28^, SRIG 33.1^, SRIG 53^, SRIG 56^, SRIG 61, SRIG 74, SRIG 81, SRIG 86, SRIG 89, SRIG 90, SRIG 102, SRIG 105, SRIG 107, SRIG 118^, SRIG 119, SRIG 124, SRIG 131, SRIG 144, SRIG 145, SRIG 148, SRIG 154, SRIG 160, SRIG 164, SRIG 178, SRIG 179, SRIG 181, SRIG 185-1.	No significant homology	AI374463^, AI374461^, AI374438^, AI376338^, AI374462^, AI374456, AI374464, AI374455, AI376315, AI374453, AI37441, AI374452, AI374451, AI374450, AI374449^, AI374448, AI374447, AI374446, AI376322, AI376323, AI376324, AI374443, AF096777, AI376330, AI374465, AI376335, AI374444, AI374445	No signal^*, other clones were not tested.
B) Identified ESTs
SRIG 8	100% with EST AA931835	AI376308 (Unigene Hs 181165)	No signal
SRIG 29	100% with EST AA027854	AI376309 (Unigene Hs 8117)	No signal
SRIG 30	100% with EST AA534569	AI376310 (Unigene Hs 13836)	No signal
SRIG-62	100% with KIAA0043 gene
SRIG 63	74% with EST AA699895	AI376312 (Unigene Hs 117353)	N.D.
SRIG 67	90% with EST AA826918	AI376313	N.D.
SRIG 80	89% with EST AA568770	AI376314	N.D.
SRIG 100	97% with EST R02820	AI376317 (Unigene Hs 31921)	N.D.
SRIG 101	99% with EST AA449652	AI376318 (Unigene Hs 11803)	N.D.
SRIG 108	80% with EST AA205076	AI374442 (Unigene Hs 17872)	N.D.
SRIG 123	94% with EST C75518	AI376319 (Unigene Hs 61184)	N.D.
SRIG 134	96% with EST AA983976	AI376320 (Unigene Hs 127105)	N.D.
SRIG 135	96% with EST AA093075	AI376321 (Unigene Hs 49015)	N.D.
SRIG 150	100% with EST AA768579	AI376326 (Unigene Hs 22549)	N.D.
SRIG 153	97% with EST AA768579	AI376327 (Unigene Hs 112227)	N.D.
SRIG 156	100% with EST AA505468	AI376329 (Unigene Hs 58609)	N.D.
SRIG 165	99% with EST AI097038	AI376331 (Unigene Hs 156103)	N.D.
SRIG 173	99% with EST AA838424	AI376333 (Unigene Hs 110978)	N.D.

A) Sequences were searched against GenBank and no significant homologies were found. Sequences were deposited in GenBank and accession numbers are indicated. B) Identification of previously identified ESTs as potential targets for retinoid modulation. GenBank accession numbers are given, as well as the Unigene family number. ND: not determined.

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