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Table 2 Maximal effect (Emax) and EC50 values for phenylephrine- and electrical stimulation induced increases in perfusion pressure in mesenteric bed and for U46619-induced contraction in aorta from control and fenofibrate-treated mice.

From: Activation of the peroxisome proliferator-activated receptor α protects against myocardial ischaemic injury and improves endothelial vasodilatation

 

Control

Fenofibrate

MESENTERIC BED

  

Phenylephrine

  

   Emax (mmHg)

22.14 ± 7.03

21.73 ± 5.55

   EC50 (M)

1.46 ± 0.5810-5

2.12 ± 0.55 10-5

 

(n = 9)

(n = 9)

Electrical stimulation

  

Emax (mmHg)

14.17 ± 1.88

15.15 ± 2.06

 

(n = 7)

(n = 9)

AORTA

  

U46619

  

   Emax (mN/mm)

4.91 ± 0.34

5.16 ± 0.37

   EC50 (M)

2.95 ± 0.85 10-8

2.8 ± 0.83 10-8

 

(n = 6)

(n = 6)