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Figure 4 | BMC Pharmacology

Figure 4

From: The orthosteric agonist 2-chloro-5-hydroxyphenylglycine activates mGluR5 and mGluR1 with similar efficacy and potency

Figure 4

Efficacy and potency of CHPG were similar for SCG calcium current modulation in cells expressing mGluR5b, mGluR1a, and mGluR1b. Calcium current inhibition by each concentration of CHPG was normalized to that by 100 μM Glu in each cell, and plotted here. Neither efficacy nor potency of CHPG’s effects on mGluR1a, 1b or 5b were statistically distinguishable.

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BMC Pharmacology

ISSN: 1471-2210