Skip to main content
Figure 1 | BMC Pharmacology

Figure 1

From: Potency, selectivity and prolonged binding of saxagliptin to DPP4: maintenance of DPP4 inhibition by saxagliptin in vitro and ex vivo when compared to a rapidly-dissociating DPP4 inhibitor

Figure 1

The effect of dilution on the IC 50 for inhibition of human plasma DPP activity by saxagliptin (Panel A) and sitagliptin (Panel B) using ala-pro-AFC as substrate (activity is measured as arbitrary fluorescence units. Mean ± s.e.m., n = 3 independent experiments, 3 replicates per experiment).

Back to article page