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Figure 1 | BMC Pharmacology

Figure 1

From: Rosiglitazone improves the natriuretic response to atrial natriuretic peptide in rats with experimental congestive heart failure: possible involvement of a post-guanylate cyclase mechanism

Figure 1

Renal RGZ-regulated genes related to ANP signalling and Na+ transport in rats with CHF. Fold-change represent comparison of CHF+RGZ vs. CHF+Veh (N=3 each). P-values for all comparisons are lower than 0.07. Averaged values for Gapdh, Ppia and Gusb were used as normalizers and the sham-control group served as the calibrator. Nos3, endothelial NO synthase; Ppp1r12a, myosin phosphatase-targeting subunit 1; Pde5/9a, cGMP-specific phosphodiesterases; Avpr2, Arginine vasopressin receptor 2; Mas1, Ang(1-7) receptor Mas; Npr3, Natriuretic peptide receptor C; Gucy1a3, soluble guanylate cyclase α1-subunit.

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